Recently, studies using a selective MOR antagonist GSK1521498 showed reductions in hedonic responses to sweetened dairy products and reduced energy intake, particularly of high‐fat foods during ad libitum buffet meals in obesity with binge eating disorder,118, 119 and reduced attentional bias for food cues on the visual dot probe task.120. This evidence concerns the gene OPRM1 and obesity due to melanocortin 4 receptor deficiency.