Most longitudinal studies did not measure changes in mood,35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53 and some found no change in mood post‐RYGB or VSG surgery33, 34, 37 or LCD47 or VLCD,36 whereas one study showed lower depression post‐RYGB surgery that was associated with a reduction in DRD2/3 availability (11C‐raclopride BP) across ventral striatum, caudate, and putamen, though no direct correlation was performed.32 This evidence concerns the gene DRD2 and depressive disorder.