On the other hand, DEGs in the PAMM1b subset mapped to GO terms associated with immune activation, cytokine production, and immune effector processes (Supplemental Figure 2E), with upregulation of ATF4, CD55, EREG, FCN1, THBS1, and MHC class I molecules (HLA-A, HLA-F) and downregulation of complement transcripts (C1QA, and C1QB) (Supplemental Figure 2F) in the maternal SARS+ group. This evidence concerns the gene C1QA and severe acute respiratory syndrome.