APOA1 and abdominal aortic aneurysm: An earlier report also identified MPO-modified Trp72 of ApoA-I as the immunogenic epitope specific for isolated dysfunctional HDL, which was associated with increased CVD risk (17), whereas oxidation of Trp at 50 and 108 positions led to a loss of vasculoprotective properties of ApoA-I in samples isolated from abdominal aortic aneurysm patients (30).