Consistent with these findings, there was a reduction in cells staining with an anti-Gr1 antibody (which recognizes activated monocytes/macrophages and granulocytes; ref. 70), but not myeloperoxidase (MPO) (which only recognizes granulocytes; ref. 71) in PTEC DN RAR mice after IRI-AKI (Supplemental Figure 15, G–I). This evidence concerns the gene MPO and acute kidney injury.