We found that ∼20% of genes that normally change in expression during infection in WT NK cells failed to change appropriately in HuR CKO NK cells, and these genes are specifically enriched for cell cycle pathway genes, potentially explaining the observed proliferation defects in NK cells upon loss of HuR (Fig. 4, C and D; and Fig. S5 A). The gene discussed is ELAVL1; the disease is infection.