Nevertheless, the expression of IL18RAP mRNA was downregulated in the following cancers: uterine carcinosarcoma (UCS), uterine corpus endometrial carcinoma (UCEC), esophageal carcinoma (ESCA), thymoma (THYM), THCA, breast invasive carcinoma (BRCA), READ, stomach adenocarcinoma (STAD), skin cutaneous melanoma (SKCM), COAD, LUAD, LIHC, prostate adenocarcinoma (PRAD), ovarian serous cystadenocarcinoma (OV), LUSC, brain lower grade glioma (LGG), acute myeloid leukemia (LAML), BLCA, KICH, lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), and adrenocortical carcinoma (ACC) (Figure 1B). The gene discussed is IL18RAP; the disease is acute myeloid leukemia.