Independent of racial composition, serum levels of C-C chemokines CCL1 (p = 0.006); CCL7 (p = 0.015), CCL8 (p = 0.001), CCL11 (p = 0.008), CCL13 (p < 0.0001), CXCL9 (p = 0.014), CXCL10 (p = 0.043), and the cytokine IL-2 (p = 0.047) and TNF-α (p = 0.005) were significantly lower in prostate cancer patients (n = 28) compared to healthy controls (n = 11). The gene discussed is CCL8; the disease is Familial prostate cancer.