Treatment of A549 cells with F. szowitsiana extract (400 μg/mL for 48 and 72 h) altered anti‐apoptosis, pro‐apoptosis and tumour suppressor gene expression, up‐regulated P53, Bax and Cas‐9 and also activated multiple apoptotic pathways and antiproliferation activity.86 This evidence concerns the gene BAX and neoplasm.