In microglial, bladder cancer and HepG2 cells, cell proliferation, migration and survival could be enhanced by up‐regulation of the Gadd45 family member Gadd45β/Myd118, which associates with MKK7/JNKK2, p38 expression, transforming growth factor‐β and TGF‐β via the JAK/STAT pathway, ultimately activating toll‐like receptors and interferon‐γin.224, 225, 226. The gene discussed is TGFB1; the disease is urinary bladder carcinoma.