LHCGR and Infertility: Luteinizing hormone/choriogonadotropin receptor (LHCGR) plays a vital role in LCs differentiation and testosterone synthesis.[5, 6] The mutation of Lhcgr causes testosterone deficiency and further contributes to impaired sexual development, arrested spermatogenesis and infertility,[7, 8, 9] thus serves as prototype of HPH.