PAX1 and Klippel-Feil syndrome 1, autosomal dominant: Most cases of KFS are sporadic and it is generally accepted that KFS is caused by several chromosomal abnormalities, including autosomal dominant inheritance: the autosomal GDF6 gene on autosome 8 [3], and the autosomal GDF3 gene on autosome 12 [4]; autosomal stealth inheritance: MEOX1 on chromosome 17 [5], and also other Several loci Hox, SGM1, and PAX1 [6, 7].