Likewise, treatment with the COX-2 inhibitor downregulated the AMP psoriasin, encoded by S100A7, in human uroepithelial cells, 5637 (Fig. 1B) and TERT-NHUC (Supplementary Fig. 2A) during non-infected state and after E. coli infection on both mRNA (Fig. 1C) and protein levels (Fig. 1D). Here, S100A7 is linked to escherichia coli infection.