CENPF and familial pancreatic carcinoma: The expression of centromere protein F (CENPF) is upregulated in pancreatic cancer [1]、esophageal squamous cell carcinoma [2] and breast cancer [3]and is involved in cell proliferation, migration, and epithelial mesenchymal transition in pancreatic cancer, and high expression of CENPF is associated with poor prognosis in pancreatic cancer patients.