In two complementary studies with NHPs that started ART later (day 14 and day 365 after infection), the combination of TLR7 agonist and one or more bNAbs tended to be associated with a lower frequency of post-intervention control (0%, 22% and 50%) than in the studies where animals started ART at day 7 or day 9 after infection25,26. This evidence concerns the gene TLR7 and infection.