INS and type 2 diabetes mellitus: Pre-specified multivariate analysis after adjusting for screening HbA1c, BMI category (BMI > 42/≤42), duration of T2DM (>5 years/<5 years), insulin use and study site showed no significant difference in HbA1c at 6 months (0.2 mmol/mol, 95%CI −11.3, 11.6 mmol/mol, p = 0.98, Supplementary Table 5.2).