We further investigated additional coding region variants from TATDN2, TMEM131L, SLCA17A1 and SLC17A3 in our cohort of 18 T1D families consisting of 37 T1D cases and 49 unaffected first-degree relatives (Table 3) based on their enrichment in T1D cohort, their segregation pattern in T1D affected versus unaffected individuals and furthermore based on the supportive evidence from the GTEx, NephQTL and T1D knowledge portal. The gene discussed is SLC17A3; the disease is type 1 diabetes mellitus.