ELAVL1 and Crohn disease: To explore the clinical relevance of HuR function in the human PC/ISC niche, human ileal mucosal tissues were collected from four Crohn’s disease (CD) patients who required urgent/emergent intestinal resection because of severe complications (SC) such as intestinal perforation, peritonitis, and necrotizing enteritis as well as four healthy controls who had neither CD, nor emergency surgical disorders.