Studies have found that NQO1 plays an important role in many human cancers, including lung, breast, uterine cervical, and prostate cancer [22–25].To explore new prognostic markers to stratify patient prognosis in the present study, we used a noninvasive radiomic model to predict NQO1 expression levels and prognosis in HCC. The gene discussed is NQO1; the disease is hepatocellular carcinoma.