IL-4 and specific antibodies were increased in cytochrome P450 IID6–induced AIH-2.25 Chi et al93 induced AIH using TLR2/4 ligand-amplified liver inflammation and found increased expression levels of the IL4 and IL13 genes and IL-4 and IL-13 proteins in the liver. The gene discussed is TLR2; the disease is autoimmune hepatitis.