AHR and autoimmune hepatitis: Elevated AhR expression also led to decreases in the Th17/Treg ratio and the activation of CD4+ T cells, CD8+ T cells, B cells, and NK cells.182 Th22 cells may be a potential therapeutic target in AIH, but more studies are needed to clarify the exact mechanism by which Th22 cells are involved in the pathogenesis and progression of AIH.