A single-cell RNA-sequencing analysis revealed that IL-22 expression was elevated in Con A-induced AIH and was further increased after treatment with the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin.182 However, ALT levels decreased after 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. This evidence concerns the gene GPT and autoimmune hepatitis.