During the epidemic period of megalomania, COVID-19-infected individuals presented with a series of nervous system symptoms, the main mechanism of which is that COVID-19 invades host cells (7) by binding to angiotensin-converting enzyme 2 and can be expressed on the surface of various nerve cells (8), causing headache, dizziness, olfactory dysfunction, cognitive impairment, convulsion, status epilepticus, paralysis, and other symptoms (9). Here, ACE2 is linked to Cognitive impairment.