IDH1 and central nervous system cancer: We downloaded nine scRNA-seq datasets of five gliomas from the GEO website, including glioblastoma (GBM), diffuse H3K27M glioma (H3K27M glioma), medulloblastoma (MB), 1p/19q codeleted oligodendroglioma (oligodendrocyte or OD), and IDH1-mutant anaplastic astrocytoma (astrocytoma or IDH1-mutant AA) (Supplementary Table S1).