TGFB1 and neoplasm: The overproduction of TGF‐β1 in the formation of a favorable microenvironment for tumor cell proliferation and metastasis, including mitigating the function of effector immune cells, promoting the generation of immunosuppressive cells, such as regulatory T cells (Tregs) and M2‐like tumor‐associated macrophages, facilitating the angiogenesis, and increasing the production of collagen, the main component of extracellular matrix in the tumors.21, 22