GPT and neoplasm: Apart from advantages such as collagen affinity, enhanced accumulation and anti-tumor efficacy that similar to previous studies, they reported reduced treatment-related toxicity of CBD modification, including water content in liver, increase of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity and other organs damage markers in C57BL/6 B16F10 allograft mouse model (44), supporting CBD to be an potential solution for adverse effects induced by therapeutic antibodies.