KDM4A and ischemic stroke: Apart from physiological functions, KDM4A is also involved in modulating several non-cancer diseases by regulating different downstream genes (Table 2), such as cardiac hypertrophy,21 atherosclerosis,22 microbial infection,23, 24, 25,43 SLE,19 ischemic stroke,44 vascular inflammation,20,45 liver fibrosis,21 and mood disorders.46