Some findings revealed overexpression of miR-29a-3p in CML-LSCs by binding to the 3′UTR region of TET2 (tet methylcytosine dioxygenase 2) and antioxidant-coding EPAS1 induced the protection of cells from imatinib mesylate (IM)-induced apoptosis.238. The gene discussed is EPAS1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.