In another cohort of fecal samples from 156 GC patients, Guo et al have shown that the combination of fecal occult blood testing composed of SDC2 methylation and TERT methylation performs well in screening for GC, with the highest sensitivity in identifying gastric stage I cancer and gastric body cancer (78.6% and 75.0%, respectively).89 The gene discussed is SDC2; the disease is gastric cancer.