Scientific evidence supports the dual functions of miR-205 as a tumor suppressor by affecting ErbB3, VEGFA, and ZEB1/2 in breast, melanoma, and lung cancers, as well as an oncogene by influencing PTEN, TRAF2, and SHIP2 in breast cancer, nasopharyngeal carcinoma, and lung squamous cell carcinoma.108. This evidence concerns the gene PTEN and lung cancer.