LUM and malignant colon neoplasm: Moreover, in colon cancer (Seya et al., 2006), liver cancer (Mu et al., 2018), neuroblastoma (Wang et al., 2017), osteosarcoma (Nikitovic et al., 2011), and chondrosarcoma (Papoutsidakis et al., 2020) among others, overexpressed LUM has been associated with worse clinical outcomes.