INS and type 1 diabetes mellitus: In 2019, the Centers for Disease Control and Prevention (CDC) estimated that there were 1.6 million people in the United States of America living with type 1 diabetes (T1D) (3) and, of these, approximately 30 to 40% use insulin pump technology (e.g. continuous subcutaneous insulin infusion (CSII) systems) to deliver insulin and manage blood glucose levels (4).