The 16SrRNA sequencing of mouse feces identified Bifidobacterium that may cause differences in tumor growth and antitumor immunity in mice; studies have also found that the Bifidobacterium can enhance DC function, leading to the initiation and clustering of CD8+ T cells in the tumor microenvironment (TME), thereby improving the antitumor immune function (115, 128, 129). Here, CD8A is linked to neoplasm.