CD8A and neoplasm: Therefore, after binding to the CD45 receptor on the inhibited leukocytes in TNBC, the C24D peptide can re-activate the Src family of tyrosine kinases, break the inhibition and trigger the intracellular signaling cascade, resulting in an increase in 69+ T cells and 69+ NK cells, inducing CD8+ and activating CD56+ tumor-infiltrating cells to achieve specific killing of TNBC cells (44).