BIRC5 and neoplasm: Studies have shown that YYVSWPPDMMHY peptide down-regulated genes related to angiogenesis (VECGF-A), proliferation-related genes (BIRC5, CDK2, and MCL1) and invasion-related genes (MMP1 and MMP7)(39), which can effectively induce apoptosis and inhibit the growth of TNBC tumor cells.