FOXA1 and non-small cell lung carcinoma: When we compared the expression of FOXA1 with gene effect (i.e., degree of essentiality/single-guide RNA dropout) across NSCLC cell lines profiled in DepMap, we found that cell lines with higher FOXA1 expression typically exhibited greater FOXA1 dependence (P = 1.6e-4, n = 82, DepMap; Fig. 1B).