In non-AMD donor eyes, DRAM2 mRNA was sparsely detected in the ganglion cell layer (GCL), the inner nuclear layer (INL), the outer nuclear layer (ONL), the retinal pigment epithelium (RPE) and the choriocapillaris (CC) (Figure 1E, top panels: representative image in the macula). The gene discussed is DRAM2; the disease is age-related macular degeneration.