Concerning DA homeostasis, a molecular docking analysis revealed that meth and amphetamine act as potential inhibitors of DA receptor for DA uptake [32] and block DA transporter (DAT) and vesicular transport and, therefore, etiologically important in the cytosolic DA mediation of neurodegeneration in PD/Parkinsonism [33]. The gene discussed is SLC6A3; the disease is Parkinson disease.