BRAF, KIT, and NRAS mutations are common mutated antigens in melanoma.259,260 Third, germline antigens are expressed in the placenta or testis as immune privilege markers.261 MAGE-A1, MAGE-A3, BAGE, GAGE, and NY-ESO-1 are cancer germline antigens that have been identified.262,263 Fourth, the term neoantigen refers to newly expressed or acquired antigens, as in genomic mutations found within tumors but not in normal somatic cells. This evidence concerns the gene BRAF and cancer.