We found that the necroptotic signaling pathway, positive regulation of necrotic cell death, regulation of sodium ion transport, and negative regulation of TNF-mediated signaling pathway were activated with GO enrichment, meanwhile, pathogen infection, Mitogen-activated protein kinase (MAPK) signaling pathway, and necroptosis were enriched via KEGG database (Fig. 1f-g). The gene discussed is WNK2; the disease is infection.