Among the 33 DEGs involved, only 9 DEGs (Cd59b, Gp1bb, Itga3, Kit, Itga2b, Il1r2, Gp5, Cd9, Gp1ba) showed upregulation whereas 24 DEGs (Ms4a1, Cd19, H2-Ab1, H2-Eb2, H2-Ob, H2-Aa, H2-Eb1, Fcer2a, H2-DMb2, H2-DMb1, Cd22, H2-Oa, Cd8b1, H2-DMa, Cd38, Cd8a, Cr2, Cd55, Cd5, Cd2, Cd1d1, Cd3d, Cd3g, Cd4) showed downregulation in HD group. The gene discussed is CD8B; the disease is Huntington disease.