GPX8 and neoplasm: As shown in Additional file 1: Figure S2, CDK1, ECT2, EZH2, GJB2, GPR37, GPX2, and GPX8 mRNA expression was up-regulated in the tumor group (p < 0.001), whereas GPX3, HYAL1, and TLR4 mRNA expression was down-regulated in the tumor group (p < 0.001) compared with those in the normal group.