The expression of CDK1, ECT2, GJB2, GPR37, GPX2, and GPX8 gene was up-regulated in the tumor group (p < 0.001), whereas the expression of TLR4 was down-regulated in the tumor group (p < 0.001) when compared with those in the normal group (Fig. 11). This evidence concerns the gene TLR4 and neoplasm.