MAPK3 and colorectal carcinoma: In addition to cerulenin, luteolin (3,4,5,7-tetrahydroxyflavone), TVB-3664, and epigallocatechin-3-gallate (EGCG) are all potential FASN inhibitors found in medicinal herbs, considered to exercise its anticancer effect in CRC via modulating multiple tumor signaling pathways, including IGF-1, AKT, STAT, Erk1/2, and Wnt-β-catenin [195–198].