VCAM-1 appears to be functionally important in the immune response and vascularization in high-grade cervical intraepithelial lesions and cervical cancer patients in several reports [30–32], and the study of its role as a molecular marker in the diagnosis of cervical diseases has been limited to histological and cytological specimens [31, 33, 34]. This evidence concerns the gene VCAM1 and cervical cancer.