Further focus on differentially expressed genes (DEGs) in OGT knockdown cells revealed decreased expression of several genes involved in glioblastoma cell proliferation, invasion and immune modulation such as IL1B, MMP1, GAP43, CXCL1, PCNA, LIF, MYC, IL6 among others (Fig. 3B). This evidence concerns the gene MMP1 and glioblastoma.