Further focus on differentially expressed genes (DEGs) in OGT knockdown cells revealed decreased expression of several genes involved in glioblastoma cell proliferation, invasion and immune modulation such as IL1B, MMP1, GAP43, CXCL1, PCNA, LIF, MYC, IL6 among others (Fig. 3B). The gene discussed is GAP43; the disease is glioblastoma.