COL5A1 and Ehlers-Danlos syndrome: Mutations in a wide variety of genes, such as TGFBR1, transforming growth factor beta receptor 2 (TGFBR2), SMADs, SMARD, COL4A3, COL4A2, COL5A1, FBN2, ACTA2, MYH11, and SKI, are associated with other Marfan-like syndromes [5], including Loeys–Dietz (LDS), Beals–Hecht (BHS), Ehlers–Danlos (EDS), Weill–Marchesani (WMS), Shprintzen–Goldberg (SGS), Stickler syndrome (StS), and Mitral Valve, Myopia, Skin, and Skeletal disorder (MASS) [6].