Obesity is associated with treatment failure (especially with anti-TNF drugs), risk of hospitalization, and lower endoscopic remission rates [16,17,18,19]; sarcopenia in overweight IBD patients (BMI ≥ 25 kg/m2) is the only significant predictor of the need for surgery (p = 0.002) [20]; nutritional deficits and low micronutrients serum levels can have a negative impact on both induction and maintenance of remission and on the quality of life of these patients [21,22]. Here, TNF is linked to inflammatory bowel disease.