For instance, decreased levels of miR-146a in brain are related to neuroinflammatory processes [78], while decreased levels of the miR-29 family (including miR-29a, miR-29b-1, and miR-29c), which regulate BACE1, favor Aβ production and accumulation, as observed in AD [78]. The gene discussed is BACE1; the disease is Alzheimer disease.