Comparison of the ALDH1A1 mRNA expression pattern in seven pancreatic cancer cell lines (BxPC3, T3M4, PANC1, SU8686, Colo-357, AsPC-1, and MiaPaCa-2) with one non-cancerous pancreatic cell line (ACBRI) showed that BxPC3, T3M4, and PANC1 exhibited minimal to no ALDH1A1 mRNA expression, whereas SU8686 and Colo-357 cells showed moderately low levels, and AsPC-1 and MiaPaCa-2 cells exhibited nine- and three-fold ALDH1A1 mRNA overexpression compared with the ACBRI cells [131]. This evidence concerns the gene ALDH1A1 and familial pancreatic carcinoma.