Additionally, ALDH18A1 seems to be overexpressed in lung cancer tissues compared with normal lung tissues [150] and is upregulated in NSCLC cell lines, A549 and the lung fibroblast cell lines, SV-80 ALDH18A1, PLOD2, and P4HA1 [151]. The gene discussed is ALDH18A1; the disease is lung carcinoma.