Τhe Sjögren-Larsson syndrome (SLS) is a neurological condition that follows an autosomal recessive pattern of inheritance and its genetic basis is a wide variety of mutations in the Aldh3a2 gene, which encodes the fatty aldehyde dehydrogenase (FALDH, Table 1) [87]. Here, ALDH3A2 is linked to Sjögren-Larsson syndrome.