For instance, in hepatocellular carcinoma, LINC01134 recruits the transcription factor SP1 to the p62 promoter to activate the antioxidant pathway of p62 [41]; lncRNA GABPB1-AS1 interacts with GABPB1 to inhibit its translation, leading to decreased PRDX5 expression and ultimately impaired antioxidant capacity of cells [42]. This evidence concerns the gene PTGDR and hepatocellular carcinoma.