CSF2 and esophageal squamous cell carcinoma: ESCC samples in the high-risk group exhibited enrichment in aspects such as “regulation of Wnt signaling pathway planar cell polarity pathway”, “DNA secondary structure binding”, “mismatch repair”, and “spliceosome”, whereas the low-risk group showed enrichment in aspects such as “positive regulation of granulocyte-macrophage colony stimulating factor production”, “an-timicrobial humoral immune response mediated by antimicrobial peptide”, “inter-leukin 1 receptor binding”, and “Toll-like receptor signaling pathway”.