The detection of the hypermethylation of the promoter region of the DNA repair gene GSTP1 (36–100% sensitivity) and cell-cycle-associated gene RASSF1a (53–96% sensitivity) [115,128] in biopsies and body fluids (serum, plasma, urine, and ejaculates) has been suggested as a sensitive and specific marker for detecting PCa. Here, GSTP1 is linked to posterior cortical atrophy.