Using SICER, Coleman et al. [325] determined the epigenetic landscape of BRD4 binding sites and identified BET bromodomain inhibitor sensitivity through MYC suppression, while Dhar et al. [326] introduced the MTA1/Epi-miR-22/E-cadherin axis as an important metastasis-promoting epigenetic signaling pathway in PCa. This evidence concerns the gene MYC and posterior cortical atrophy.