MET and neoplasm: Other approaches to reduce tumor burden in C3-TAg mice, including treatments with cytotoxic chemotherapy drugs (carboplatin, paclitaxel, and polyethylene glycol-tagged liposomal doxorubicin), kinase inhibitors (erlotinib and lapatinib), cMET inhibitors, and dietary supplementation with flavonol, have been unable to significantly extend lifespan or reduce tumor growth [68,69].