AFP and rhabdoid tumor: However, the Children’s Hepatic Tumors International Collaboration (CHIC), after analyzing its databases and identifying SMARCB1 mutations in a group of HBs with the small cell undifferentiated subtype or HBs with low AFP levels (with survival rates of 24–37.5%), concluded that some of these HBs were rhabdoid tumors with an extremely unfavorable prognosis (3-year OS—0%).