Until recently, AFP was used as a simple diagnostic tool for Fanconi anemia (FA), with studies indicating varied sensitivity: 93% sensitivity and 100% specificity (Cassinat et al., 2000) [37]; 46% sensitivity (Aslan et al., 2002) [19]; and 71% sensitivity (Salem et al., 2019) [17]. The gene discussed is AFP; the disease is Friedreich ataxia.