Because macrophage-ROS and TNF/TNFR2/NF-κB play a role that affects Treg cell induction associated with ADC burdens in Ikka∆LU;KrasG12D mice, we further analyzed the expression of the associated genes to determine the relevance of this pathway in human lung ADC cohorts (cBioPortal for Cancer Genomics). The gene discussed is TNF; the disease is AIDS dementia complex.