The outcome was that the top six risk factors rank as follows, using PSA as primary biomarker [25]: age > PCa-fh (family history of prostate cancer) > diabetes ≥ race > lifestyle (smoking and coffee consumption) ≥ marital status ≥ BMI > X, in which X represented a specific diet nutrient/ingredient metric. Here, KLK3 is linked to Familial prostate cancer.